This paper describes a methodical and practical approach of hybrid model creation using the simulation tool AnyLogic. We focus on general modeling aspects and on advanced techniques using a Level-Based Architecture that help to develop large scale hybrid simulation models. An implementation of a stroke therapy use-case and its simulation results will be discussed. Finally, some practical ideas for validation will be outlined, as we experienced during the stroke use-case development.
AnyLogic è un ambiente di modellazione virtuale di sistemi discreti, continui ed ibridi. Con questo strumento è possibile creare prototipi di sistemi durante le fasi di studio, progettazione o sviluppo, attraverso cui esplorare aspetti e dettagli della progettazione o della implementazione dei relativi sistemi in modo semplice e privo di rischi
This interdisciplinary research focuses on improving the oral health of older adults as a means of enhancing their overall wellbeing and quality of life. Periodontal disease is a risk factor for other chronic illnesses, notably diabetes and cardiovascular disease. In order to identify policies that improve oral health for older adults, a dynamic modeling approach that considers community and individual level factors is utilized.
A simulation model called VirSim was developed to aid policy making in Sweden. The model simulates the spread of pandemic influenza, using real population data on a national and regional level. Swedish authorities wanted a model that was both quick to run and to implement as a complement to the existing model MicroSim.
Emergency Departments (EDs) require advanced support systems for monitoring and controlling their processes: clinical, operational, and financial. A prerequisite for such a system is comprehensive operational information (e.g. queueing times, busy resources,…), reliably portraying and predicting ED status as it evolves in time. To this end, simulation comes to the rescue, through a two-step procedure that is hereby proposed for supporting real-time ED control.
By creating an integrated simulation environment that models the underlying structure of a pharmaceutical enterprise portfolio it becomes possible to identify the optimal longitudinal allocation of finite resources across the constellation of available investment opportunities. The implementation of a hybrid approach that integrates multiple modeling techniques and analytic disciplines allows for a comprehensive environment that captures the underlying dynamics that drive observed market behavior. The implementation of an object oriented model structure constrains the models complexity by supporting dynamic re-use of both structure and logic.
In recent US Census data widely reported in the press “Hispanics” have become the largest minority group in the US. Using simulation modeling technology we look at some of the structural forces that shape the characteristics of the Hispanic population. The model creates a simulated Hispanic population whose level of acculturation to the broader population of which it is a part dynamically varies according to individual choice. The modeling technique used draws on both System Dynamic and Agent based paradigms both supported by innovative AnyLogic software. The representative Hispanic population is disaggregated down to the individual level as individual agents. Each agent makes choices stochastically as modulated by its current state and the outside environment that it is in.
Mathematical modeling is a relatively new but fast developing area of HIV studies providing researchers with an additional dynamical dimension in epidemiological work that allows scientists to simulate the consequences of various intervention and prevention scenarios. We illustrate these concepts by presenting a model that describes Injecting Drug Users (IDU) networks, injecting behavior and HIV/HCV spread within the networks. This individual-based (also called agent-based) model is used to investigate the impact of the introduction of Integralcannula syringes (ICS) instead of commonly used Detachable Needle syringes (DNS). Laboratory experiments have shown that ICS retain approximately 1000 times less residual blood (<.001 ml vs. 1ml) following injection and rinsing than DNS thereby decreasing risk of HIV/NCV transmission by nearly 100 times after 2 rinses.
Mathematical modeling is a relatively new but fast developing area of substance use field providing researchers with additional dynamical dimension in epidemiological work and allowing scientists to simulate the consequences of various intervention and prevention scenarios. We illustrate these concepts by presenting two models. The first model describes Injecting Drug Users (IDU) networks, injecting behavior and HIV/HCV spread among the networks. The size, structure of the networks as well as frequency of injecting and HIV risks were obtained from published literature on urban IDU networks. This individual-based model was used to investigate the impact of introduction of Integral-cannula syringes (ICS) instead of commonly used Detachable Needle syringes (DNS).
This paper explores the problem of fragmenting social networks enabled by spatial distancing between distinct socioeconomic classes. Such fragmentation is evidenced by the experience of urban sprawl without population growth. We develop a prototype model to examine the spatial dynamics of social network evolution in the face of neighborhood migration. This model draws upon the small world analogy by using an initial template of connections that are “rewired” over time. Spatially, connections are established for neighborhood proximity. Socially, connections are added based upon similarity of economic class.