Airports are intermodal hubs and natural interfaces between ground transport and air transport. In the current DLR project “Optimode.net”, an innovative approach is being developed to extend the management of an airport not only to airport landside and terminal processes but to go even further and incorporate feeder traffic in the management of airport processes. Thus providing travelers with a real door-to-door service and letting airport stakeholders benefit from efficient airport management. Technical core of the project is a simulation environment consisting of nine different simulation models with various simulation methods and abstraction levels. In this paper the simulation environment of a multi airport region which is used in the Optimode.net project will be described in detail and also the interaction of the different simulation modules will be explained. We will also show how this complex simulation environment is used to foster individual door-to-door travel and proactive airport management.