Academic articles

Simulation Model of a Multi-Hospital Critical Care Network


A discrete event simulation model was developed for a network of eight major intensive care units (ICUs) as well as high-acuity units (HAUs) in British Columbia, Canada. The simulation model will be used to develop strategies for managing the combined impacts of COVID-19 and seasonal influenza without the need for extensive public health interventions to limit transmission.

A Tutorial on How to Set Up a System Dynamics Simulation on the Example of Covid-19 Pandemic


The Covid-19 virus has substantially transformed many aspects of life, impacted industries, and revolutionized supply chains all over the world. System dynamics modeling can aid in predicting future outcomes of the pandemic and generate key learnings. This tutorial describes how the system dynamics simulation model was constructed for the Covid-19 pandemic using AnyLogic Software. The model serves as a general foundation for further epidemiological simulations and system dynamics modeling.

Agent-Based Simulation to Predict Occupants’ Physical-Distancing Behaviors in Educational Buildings


Physical distancing is recommended as the most efficient strategy for defending individuals from long-term global pandemics. It lowers the risk of community spreading, especially for indoor spaces. This paper aims to model physical-distancing behaviors in an educational facility, using agent-based simulation, and evaluate the impact of measures (e.g., controlling classroom capacity, breaktime scheduling) on physical distance violation risks.

Simulation of epidemic trends for a new coronavirus under effective control measures


In December 2019, there was a case of viral pneumonia in Wuhan. After confirming that the pathogen of this disease is a new coronavirus, the World Health Organization (WHO) confirmed and named it 2019-nCoV. The pneumonia caused by this pathogen infection is called a novel corona virus pneumonia.

To better understand the mode of transmission of 2019-nCoV among the population and the effects of control measures, the study was conducted using agent-based modeling (ABM) to simulate an interactive environment over a certain space-time range. The study simulates the trend of 2019-nCoV infection at different levels of close contact in order to provide relevant information and references.

Evaluation of Outbreak Response Immunization in the Control of Pertussis Using Agent-based Modeling


Pertussis control remains a challenge due to recently observed effects of waning immunity to acellular vaccine and suboptimal vaccine coverage. Multiple outbreaks have been reported in different ages worldwide. For certain outbreaks, publichealth authorities can launch an outbreak response immunization (ORI) campaign to control pertussis spread. The authors developed an agent-based model to investigate effects of outbreak response immunization campaigns targeting young adolescents in averting pertussis cases. The experience proved that ABM offers a promising methodology to evaluate other public health interventions used in pertussis control. The authors also identified the strong need for further research into application of modeling to further our understanding of pertussis epidemiology.

Hybrid Simulation in Healthcare: New Concepts and New Tools


Until relatively recently, developing hybrid simulation models using more than one simulation paradigm was a challenging task which required a degree of ingenuity on behalf of the modeler. Generally speaking, such hybrid models either had to be coded from scratch in a programming language, or developed using two (or more) different off-the-shelf software tools which had to communicate with each other through a user-written interface. Nowadays a number of simulation tools are available which aim to make this task easier. This paper does not set out to be a formal review of such software, but it discusses the increasing popularity of hybrid simulation and the rapidly developing market in hybrid modeling tools, focusing specifically on applications in health and social care and using experience from the Care Life Cycle project and elsewhere.

Agent-based population model used to identify and evaluate dog population management strategies


Developing countries are faced with finding novel and humane ways to permanently reduce and control their dog population. Agent-based models developed to describe dog populations represent a unique, platform for using computer based simulation to identify control strategies with the greatest potential for success, aid in the design of more effective control measures, and provide a means to evaluate the success of different interventions.

A Plant-Level, Spatial, Bioeconomic Model Of Plant Disease Diffusion And Control: Grapevine Leafroll Disease


Grapevine leafroll disease threatens the economic sustainability of the grape and wine industry in the United States and around the world. This viral disease reduces yield, delays fruit ripening, and affects wine quality. Although there is new information on the disease spatial-dynamic diffusion, little is known about profit-maximizing control strategies. Using cellular automata, we model the disease spatial-dynamic diffusion for individual plants in a vineyard, evaluate nonspatial and spatial control strategies, and rank them based on vineyard expected net present values.

A Tripartite Hybrid Model Architecture for Investigating Health and Cost Impacts and Intervention Tradeoffs for Diabetic End-stage Renal Disease


Like most countries, Canada faces rising rates of diabetes and diabetic ESRD, which adversely affect cost, morbidity/mortality and quality of life. These trends raise great challenges for financial, human resource and facility planning and place a premium on understanding tradeoffs between different intervention strategies. We describe here our hybrid simulation model built to inform such efforts.

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